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Abstract #2468

Proton-Density Fat Fraction measurement: A Viable Quantitative Biomarker for Differentiating Adrenal Adenomas from Nonadenomas

Xiaoyan Meng1, Xiao Chen1, Yaqi Shen1, Zhen Li1, Xuemei Hu1, Hui Lin2, and Daoyu Hu1

1raidology, Tongji hospital, Tongji medical college, Huazhong university of science and technology, Wuhan,Hubei province, China, People's Republic of, 2GE Healthcare, Wuhan,Hubei, China, People's Republic of

The aim of our study was to compare the accuracy of PDFF measurements and conventional IP/OP images for quantifying the fat content of adrenal gland nodules and for distinguishing adenomas from nonadenomas.Our results showed that PDFF imaging provided almost accuracy compared with IP/OP imaging.PDFF could be a simpler diagnostic tool for discriminating adenomas from nonadenomas, with a high sensitivity and a relatively high specificity, thus avoiding complicated data calculations. This technique is potentially a helpful and a widely applicable method for diagnosing adrenal gland nodules in clinical studies.

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