Abstract #2468

Proton-Density Fat Fraction measurement: A Viable Quantitative Biomarker for Differentiating Adrenal Adenomas from Nonadenomas

Xiaoyan Meng¹, Xiao Chen¹, Yaqi Shen¹, Zhen Li¹, Xuemei Hu¹, Hui Lin², and Daoyu Hu¹

¹raidology, Tongji hospital, Tongji medical college, Huazhong university of science and technology, Wuhan,Hubei province, China, People's Republic of, ²GE Healthcare, Wuhan,Hubei, China, People's Republic of

The aim of our study was to compare the accuracy of PDFF measurements and conventional IP/OP images for quantifying the fat content of adrenal gland nodules and for distinguishing adenomas from nonadenomas.Our results showed that PDFF imaging provided almost accuracy compared with IP/OP imaging.PDFF could be a simpler diagnostic tool for discriminating adenomas from nonadenomas, with a high sensitivity and a relatively high specificity, thus avoiding complicated data calculations. This technique is potentially a helpful and a widely applicable method for diagnosing adrenal gland nodules in clinical studies.

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