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Abstract #2469

Three-time point method of dynamic contrast-enhanced MRI in discrimination of  ACTH-producing and non-functional pituitary adenomas based on whole-tumor quantification

Miaomiao Wang1, Chao Jin1, Jianxin Guo1, Lihong Chen1, Tingting Qu1, Hui Hao1, and Jian Yang1

1Department of Radiology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China, People's Republic of

Quantitative characterizations of functional vascularity of ACTH-producing and non-functioning pituitary adenomas are critical to identify their differences in clinics. From this, a semi-quantitative method, i.e. three-time point method of DCE-MRI was proposed to detail the dynamic enhanced features and thus distinguish them. The results indicate that based on the enhancement time-signal curve, the volume percentage of the two groups are different in the washout-type curve. Particularly, in wash-out phase of the curve, the descending slope of ACTH-producing is greater than that in non-functioning pituitary adenoma.

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