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Abstract #2471

Co-registration of pre-biopsy and biopsy MRIs to facilitate lesion localization for MR-guided breast biopsies

Mirabela Rusu1, Elizabeth A. Morris2, Elizabeth J. Sutton2, and Ileana Hancu1

1GE Global Research, Schenectady, NY, United States, 2Memorial Sloan Kettering Cancer Center, New York, NY, United States

Lesion identification in MR-guided biopsy exams can be hampered by many factors, including large deformations and limited tissue perfusion due to breast compression. Multiple post-contrast scans, image subtraction and maximum intensity projection map generation may be needed to relocate the lesion. This preliminary study suggests that non-rigid registration between the (uncompressed breast) pre-biopsy series and the (compressed breast) biopsy series may facilitate fast and accurate lesion (re)localization, even with limited/absent lesion enhancement.

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