Abstract #2483

Influence of fat suppression to evaluate T1 values in breast cancer: assessing the reliability of pharmacokinetic parameters

Kayu Takezawa¹, Mariko Goto¹, Koji Sakai¹, Hiroyasu Ikeno¹, Katsuhiko Nakatsukasa², Hiroshi Imai³, and Kei Yamada¹

¹Radiology, Kyoto Prefectural University of Medicine, Kyoto, Japan, ²Breast Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan, ³Siemens Japan K.K, Tokyo, Japan

The influence of fat suppression on T1 values and pharmacokinetic parameters in breast cancer were evaluated using a prototype Dixon-TWIST-VIBE technique. We measured T1 values of breast cancers on both fat suppression and not-fat suppression data sets and we calculated K^trans values using same ROI that employed on T1 value measurements. Our result suggests that the fat suppression might influence T1 values in breast cancer, and reliability of K^trans seemed inappropriate as an absolute value. On the other hand, the assessment of intra-patient K^trans change might be feasible.

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