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Abstract #2489

Luminal water imaging: a novel MRI method for prostate cancer diagnosis

Shirin Sabouri1, Silvia Chang2,3, Richard Savdie4, Jing Zhang5, Edward Jones6, Larry Goldenberg4,7, and Piotr Kozlowski2,4,5,7

1Physics and Astronomy, University of British Columbia, Vancouver, BC, Canada, 2Radiology, University of British Columbia, Vancouver, BC, Canada, 3Vancouver General Hospital, Vancouver, BC, Canada, 4Urologic Sciences, University of British Columbia, Vancouver, BC, Canada, 5UBC MRI Research Center, Vancouver, BC, Canada, 6Pathology, Vancouver General Hospital, Vancouver, BC, Canada, 7Vancouver Prostate Centre, Vancouver, BC, Canada

MR multi-exponential T2 mapping can be used for extracting valuable information about tissue composition in prostate. Using this technique, the fractional volume of the luminal space in the prostatic tissue can be determined. Since tissue composition and the amounts of lumen differ between normal and cancerous tissues, this technique can be applied for detection of prostatic tumors. We have investigated the suitability of using MR multi-exponential T2 mapping for detection and staging of prostate cancer. We have acquired and analyzed MR images of 11 patients, and concluded that this technique is highly sensitive and specific in detection of prostatic tumors.

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