Abstract #2490

Comparison of PIRADS v1.0 and v2.0 for MRI detection of prostate cancer: preliminary findings in patients with whole-mount histological workup

Josephin Otto¹, Alexander Schaudinn¹, Simone Mucha¹, Nicolas Linder¹, Nikita Garnov¹, Jens-Uwe Stolzenburg², Lars-Christian Horn³, Thomas Kahn¹, Michael Moche¹, and Harald Busse¹

¹Diagnostic and Interventional Radiology Department, Leipzig University Hospital, Leipzig, Germany, ²Urology Department, Leipzig University Hospital, Leipzig, Germany, ³Institute of Pathology, University of Leipzig, Leipzig, Germany

Multiparametric MRI of the prostate has substantially improved the detection of clinically significant prostate cancer (PCa) and the confidence in benign and insignificant findings. The recent v2.0 update of the Prostate Imaging Reporting and Data System (PIRADS) has replaced the sum of individual MRI sequence scores (1-15 or 1-20) with a zone-dependent, dominant MRI sequence (DWI in the peripheral and T2W in the transition zone) with an overall score from 1-5. The aim of this preliminary study was the blinded comparison of both versions for the detection of PCa on the same patients using whole-mount histological workup as gold standard.

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