Abstract #2521

MR visible localization device for ex vivo radiographic-pathologic correlation

Sonja Kinner^1,2, Tilman B Schubert^1,3, Christopher Brace¹, Elisabetta A Nocerino¹, Timothy J Colgan¹, Shannon Hynes¹, Scott B Reeder^1,4,5,6,7, and Emily R Winslow⁸

¹Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States, ²Department of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Essen, Germany, ³Clinic for Radiology and Nuclear Medicine, Basel University Hospital, Basel, Switzerland, ⁴Department of Medical Physics, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States, ⁵Department of Emergency Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States, ⁶Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States, ⁷Department of Biomedical Engineering, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States, ⁸Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States

In this work we describe the design and preliminary validation of a novel MR-compatible localization device aimed at facilitating lesion detection in ex vivo tissue, such as resected liver. Experiments in two swine liver specimens with small microwave ablations to simulate lesions demonstrated the successful feasibility and ease of use of this localization device. Further evaluation in human liver tissue specimens containing metastatic lesions will be needed to demonstrate the performance of the device for ex vivo radiographic-pathologic correlation.

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