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Abstract #2552

Quantitative Susceptibility Mapping of Atherosclerosis in Carotid Arteries

Chaoyue Wang1, Saifeng Liu2, Sagar Buch2, Hyun Seok Choi3, Eo-Jin Hwang3, Zhaoyang Fan4, and E. Mark Haacke1,2,5,6

1School of Biomedical Engineering, McMaster University, Hamilton, ON, Canada, 2The MRI Institute for Biomedical Research, Waterloo, ON, Canada, 3Department of Radiology, St. Mary’s Hospital, Seoul, Korea, Republic of, 4Department of Radiology, Cedars Sinai Hospital, Los Angeles, CA, United States, 5Department of Radiology, Wayne State University, Detroit, MI, United States, 6Biomedical Engineering, Northeastern University, Shenyang, China, People's Republic of

Due to complex structures in neck, such as the presence of bone and air, existing methods for neck quantitative susceptibility mapping (QSM) have several limitations. The purpose of this study was to find a reliable method for data collection in order to use QSM to detect carotid plaque and recognize vulnerable features. Therefor, we proposed a multi-echo SWI approach for data collection and regional 2D polynomial fitting method for data processing. Preliminary results show this method is able to image the vessel wall clearly and recognize calcified atherosclerosis and thrombosis by their susceptibility value.

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