Abstract #2552

Quantitative Susceptibility Mapping of Atherosclerosis in Carotid Arteries

Chaoyue Wang¹, Saifeng Liu², Sagar Buch², Hyun Seok Choi³, Eo-Jin Hwang³, Zhaoyang Fan⁴, and E. Mark Haacke^1,2,5,6

¹School of Biomedical Engineering, McMaster University, Hamilton, ON, Canada, ²The MRI Institute for Biomedical Research, Waterloo, ON, Canada, ³Department of Radiology, St. Mary’s Hospital, Seoul, Korea, Republic of, ⁴Department of Radiology, Cedars Sinai Hospital, Los Angeles, CA, United States, ⁵Department of Radiology, Wayne State University, Detroit, MI, United States, ⁶Biomedical Engineering, Northeastern University, Shenyang, China, People's Republic of

Due to complex structures in neck, such as the presence of bone and air, existing methods for neck quantitative susceptibility mapping (QSM) have several limitations. The purpose of this study was to find a reliable method for data collection in order to use QSM to detect carotid plaque and recognize vulnerable features. Therefor, we proposed a multi-echo SWI approach for data collection and regional 2D polynomial fitting method for data processing. Preliminary results show this method is able to image the vessel wall clearly and recognize calcified atherosclerosis and thrombosis by their susceptibility value.

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