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Abstract #2562

Sensitivity of cardiac magnetic resonance imaging to fluid shifts induced by an external leg compression device

Salvatore Saporito1, Ingeborg H.F. Herold 1,2, Silviu Dovancescu3, Jacques A. den Boer1, Ronald M. Aarts1,3, Arthur R. Bouwman2, Harrie C.M. van den Bosch4, Hendrikus H.M. Korsten 1,2, Hans C. van Assen1, and Massimo Mischi1

1Department of Electrical Engineering, Eindhoven University of technology, Eindhoven, Netherlands, 2Department of Anesthesiology and Intensive Care, Catharina Hospital Eindhoven, Eindhoven, Netherlands, 3Philips Research, Eindhoven, Netherlands, 4Department of Radiology, Catharina Hospital Eindhoven, Eindhoven, Netherlands

The assessment of thoracic fluid status is crucial for diagnosis, management, stratification, and follow-up of heart failure patients. Indicator dilution theoretical framework allows absolute volume estimation; magnetic resonance contrast agents have been proposed as indicators, with the advantage of a non-invasive detection. In this pilot study, we investigated the changes in intra-thoracic blood volume (ITBV) measured by cardiac magnetic resonance during fluid shifts induced by a pneumatic leg compression device. Preliminary results on 8 healthy volunteers suggest the sensitivity of the proposed measurement technique; a significant increase in ITBV after the leg compression was observed.

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