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Abstract #2617

Impaired myocardial resting perfusion in patients undergo chemo therapy, a quantitative MRI perfusion study

Yi Wang1

1St. Francis Hospital, Albertson, NY, United States

We tried to develop and validate an early detection technique of chemo therapy cardiotoxicity in the cancer treatment using cardiovascular magnetic resonance imaging. We hypothesized myocardial blood flow (MBF), more sensitive technique than EF or DHE, provides information on the altered physiology and function conditions of the heart. Chemo treatment induces changes in myocardial perfusion at rest enough to be detected with model based quantitation, with sequential imaging on the same subject. It provides an earlier indication of cardiotoxicity.

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