Abstract #2618

4D-PC MRI Pressure Mapping for Therapy Planning of Coarctation of the Aorta

Anja Hennemuth¹, Christian Schumann¹, Mathias Neugebauer¹, Hanieh Mirzaee¹, Sarah Nordmeyer², Marcus Kelm², Leonid Goubergrits², and Titus Kühne²

¹Fraunhofer MEVIS, Bremen, Germany, ²Department of Congenital Heart Disease / Pediatric Cardiology, German Heart Center Berlin, Berlin, Germany

The induced pressure gradient due to the vessel narrowing associated with coarctation of the aorta is a crucial parameter for treatment planning. Previous studies have shown that pressure differences derived from 4D PC MRI correlate well with conventional pressure catheter measurements. The purpose of the presented work was to investigate how MRI-based pressure maps can be employed in treatment planning of coarctation of the aorta. To this end, a combined 3D maximum value projection, which highlights relative value changes with respect to a reference point, and a curve diagram showing the pressure course along the centerline are provided for interactive exploration. Two cardiologists retrospectively explored 5 datasets of patients with treated coarctation of the aorta. The pressure gradient derived from the 4D PC MRI measurement corresponded well with the interventional measurements. Furthermore, additional relevant information could be derived regarding the location of the critical vessel sections. These findings show the potential of 4D PC MRI pressure mapping as a useful non-invasive tool for treatment planning of coarctation of the aorta.

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