Abstract #2620

Accelerated MR Elastography for Quantitative Measurement of Myocardial Stiffness

Rizwan Ahmad¹, Samuel Schroeder², Richard D White³, and Arunark Kolipaka³

¹Electrical and Computer Engineering, The Ohio State University, Columbus, OH, United States, ²Mechanical Engineering, The Ohio State University, Columbus, OH, United States, ³Radiology, The Ohio State University, Columbus, OH, United States

Alterations in myocardial stiffness have been linked to wide-ranging cardiovascular conditions. Magnetic resonance elastography (MRE) is a noninvasive, quantitative technique to estimate stiffness of soft tissue.1 Long scan times, however, limit the clinical utility of MRE, especially for cardiac imaging. We propose a data processing technique that not only exploits sparsity in the MRE images but also imposes a constant magnitude constraint to achieve accurate stiffness values from highly undersampled data. The method is validated using a physical phantom of known stiffness value and is then applied to a healthy volunteer to assess myocardial stiffness.

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