Abstract #2669

Characterization of carotid plaque using sampling perfection with application-optimized contrast using different flip angle evolution (SPACE) sequence

Yoshimitsu Ohgiya¹, Nobuyuki Ohike ², Naomi Yagi ¹, Hiroto Sasamori¹, Jiro Munechika ¹, Masanori Hirose ¹, and Takehiko Gokan ¹

¹Showa University School of Medicine, Tokyo, Japan, ²Department of Pathology, Showa University Fujigaoka Hospital, Yokohama-shi, Japan

The purpose of this study was to investigate whether 3D turbo spin-echo (TSE) SPACE sequence can evaluate plaque characteristics of the carotid artery. Mann-Whitney test was used to examine differences in the contrast ratio (CR) between soft plaques and fibrous plaques on T1- and T2-weighted images. The mean CR of the soft plaques (1.54 ± 0.25) was significantly higher than that of the fibrous plaques (1.17 ± 0.13) (p < 0.001) on T1-weighted images. In conclusion, T1-weighted TSE SPACE sequence can evaluate main components of plaques in the carotid artery with high sensitivity and specificity.

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