Natsuko Onishi1, Masako Kataoka1, Shotaro Kanao1, Mami Iima1, Makiko Kawai1, Akane Ohashi1, Katsutoshi Murata2, Benjamin Schmitt3, and Kaori Togashi1
1Dept of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan, 2Research & Collaboration Dpt., Siemens Japan K.K., Tokyo, Japan, 3Healthcare Sector, Siemens Ltd, Melbourne, Australia
Amide proton transfer (APT) imaging is the representative endogenous
chemical exchange saturation transfer (CEST) imaging that has been applied to
some clinical cancer studies. However, little is known about the clinical
usefulness of APT imaging in breast cancer. In this study, 3T MRI studies
including APT imaging were performed for 24 breast cancer lesions, and the possible
utility of APT imaging in evaluating biochemical information induced by breast
cancer was demonstrated. APT CEST imaging is a potentially useful MRI technique
for breast cancer.
