Abstract #2736

Quantitative magnetic resonance imaging of lymphatic function before and after manual lymphatic drainage in patients with breast cancer treatment-related lymphedema

Paula M.C. Donahue¹, Allison O. Scott², Rachelle Crescenzi², Aditi Desai², Vaughn Braxton², and Manus J. Donahue²

¹Physical Medicine and Rehabilitation, Vanderbilt University Medical Center, Nashville, TN, United States, ²Radiology, Vanderbilt University Medical Center, Nashville, TN, United States

The overall goal of this work is to develop quantitative biomarkers of lymphatic system structure and function using noninvasive 3T MRI. Here, we focus on breast cancer treatment-related lymphedema (BCRL) where we hypothesize quantitative T2 is elevated in patients relative to controls resulting from greater fluid content in the region of interests, and which reduces following manual lymphatic drainage (a commonly performed therapy intervention). Findings suggest abilities to detect changes consistent with intervention-elicited lymphatic dynamics by using internal measures of tissue composition from MRI otherwise not detected using more common limb volume, bioimpedance spectroscopy and tissue dielectric constant measures.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.