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Abstract #2744

Diffusion and Perfusion Coefficients of Prostate Cancer: Using Intravoxel Incoherent Motion Bi-exponential model

Yu Guo1, Penghui Wang1, Xiaodong Ji1, Chao Chai1, Yu Zhang2, and Wen Shen1

1Department of Radiology, Tianjin first center hospital, Tianjin, China, People's Republic of, 2Philips Healthcare, Beijing, China, People's Republic of

The purpose of the study was to investigate the diffusion and perfusion coefficients among prostate cancer(PCa), normal peripheral zone (PZ) and benign prostatic hyperplasia (BPH) using the IVIM technique. The IVIM was performed at 11 b values of 0, 10, 20, 30, 50, 75, 100, 250, 500, 750 and 1000s/mm2. The perfusion fractions in prostate cancer were significantly higher than those found in the PZ and lower than BPH, which different with some studies. But our results are more consistent with some DCE-MRI studies in tumors Future work will recruit more volunteers and subjects and combined with DCE-MRI for further validation.

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