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Abstract #2746

Feasibility Study of 3-T diffusion tensor imaging of the prostate transition zone: fractional anisotropy Versus apparent diffusion coefficient

Zan Ke1 and Liang Wang1

1Radiology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan,China, China, People's Republic of

This study is to investigate the diagnostic utility of fractional anisotropy(FA) and apparent diffusion coefficient(ADC) values of diffusion tensor imaging(DTI) to differentiate and classify abnormal signal nodules in prostate transition zone. Eighty-four patients were included in our study and divided into 5 groups: BPH,Gleason score(GS)≤6,GS=7,GS=8,GS≥9,measured FA and ADC of the region of interest, using one-way ANOVA to compare the difference among groups. There was significant statistical difference between the groups of FA and ADC values(F=20.986,P=0.000; F=26.560,P=0.000).Comparison among five groups: just BPH had significant statistical difference(P=0.000) with other four groups. The FA and ADC values of DTI had higher value for distinguishing benign and malignant nodules, but no obvious advantages in the further classification.

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