This study is to
investigate the diagnostic utility of fractional anisotropy(FA) and apparent
diffusion coefficient(ADC) values of diffusion tensor imaging(DTI) to differentiate and classify abnormal signal
nodules in prostate transition zone. Eighty-four patients were included in our study and divided
into 5 groups: BPH,Gleason score(GS)≤6,GS＝7,GS＝8,GS≥9,measured FA and ADC of the
region of interest, using one-way ANOVA to compare the difference among groups. There
was significant statistical
difference between the groups of FA and ADC values(F＝20.986,P＝0.000; F＝26.560,P＝0.000).Comparison among five groups: just BPH
had significant statistical difference(P＝0.000) with other four groups. The FA and ADC values of DTI had higher
value for distinguishing benign and malignant nodules, but no obvious
advantages in the further classification.
