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Abstract #2758

Consistent T1 Quantification in a Multiscanner Setting using Reference Region Variable Flip Angle B1+ Mapping

Novena Rangwala1, Isabel Dregely1, Holden Wu1, and Kyunghyun Sung1

1Department of Radiological Sciences, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, United States

The purpose of this study was to demonstrate improved T1 estimation in the prostate using the Reference Region Variable Flip Angle (RR-VFA) B1+ mapping and correction across multiple MRI scanners with different RF transmission modes. Prostate T1 measurements were compared in four volunteers on three MRI scanners before and after B1+ correction. The results showed that, for each volunteer, T1 variations across scanners decreased by 62% after RR-VFA correction, to an average of 10% among scanners, highlighting the need for B1+ correction and the ability to effectively yield precise T1 estimations in a multi-scanner setting using RR-VFA.

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