Abstract #2785

Imaging of Nuclear Overhauser Enhancement in Human Brain Tumor at 3 Tesla

Yuanyu Shen¹, Gang Xiao², Zhiwei Shen¹, Xiaolei Zhang¹, Wei Hu¹, Xiangyong Tang¹, Zhiyan Zhang¹, Jitian Guan¹, and Renhua Wu¹

¹2nd Affilicated Hospital, Shantou University Medical College, Shantou, China, People's Republic of, ²Hanshan Normal University, Chaozhou, China, People's Republic of

Our aim was to demonstrate the feasibility of nuclear Overhauser enhancement (NOE) imaging to detect the characteristic of patients with brain tumors. Six healthy volunteers and eleven patients with brain tumors were recruited for undergoing MRI scan at 3T. As a result, we found NOE value was greater in white matter compared to gray matter. However, in human brain tumors, NOE value was slightly hypointense in glioma and little difference in meningioma. NOE imaging may help to distinguish the heterogeneity of benign or malignant tumors, and it is important in diagnosis and treatment planning for patients with brain tumors.

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