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Abstract #2819

Comparison of Signal intensity measures with absolute T1 value quantification in patients undergoing serial follow up imaging in patients with neurocysticercosis

Pradeep Kumar Gupta1, Prativa Sahoo2, Alok Kumar Singh3, Ravindra Kumar Garg3, Rupsa Bhattacharjee4, and Rakesh Kumar Gupta1

1Radiology and Imaging, Fortis Memorial Research Institute, Gurgaon, India, 2Healthcare, Philips India ltd, Bangalore, India, 3Department of Neurology, KG Medical University, Lucknow, India, 4Healthcare, Philips India ltd, Gurgaon, India

Gadolinium based contrast agents are necessary for MRI for disease detection and therapy. Studies reported gadolinium remains in brain for long time after injecting contrast particularly in follow up patients undergoing serial contrast applications. T1 signal intensity increases slowly due to contrast accumulation in brain. Our study quantifies T1 relaxation time as a measure for follow up contrast patients. Results show absolute T1 significantly decreases in Gray Matter regions, putamen, thalamus and globus pallidus. We conclude that absolute T1 quantification can efficiently pick up deposition of gadolinium much earlier than T1 signal intensity changes as observed in Gray matter regions.

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