Abstract #2823

Relaxation Properties of Human Umbilical Cord Blood at 1.5 Tesla

Sharon Portnoy¹, Mark Osmond², Meng Yuan Zhu³, Mike Seed⁴, John G. Sled^1,2,5, and Christopher K. Macgowan^1,4

¹Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada, ²Department of Obstetrics and Gynaecology, University of Toronto, Toronto, ON, Canada, ³Institute of Medical Science, University of Toronto, Toronto, ON, Canada, ⁴Diagnostic Imaging, The Hospital for Sick Children, Toronto, ON, Canada, ⁵Mouse Imaging Centre, The Hospital for Sick Children, Toronto, ON, Canada

Relaxometry measurements were performed on umbilical cord blood samples (N=88) spanning a broad range of hematocrits (0.19<Hct<0.76) and oxygen saturations (4%<sO₂<100%). Simple biophysical models were used to describe variations in T₁ and T₂ as a function of these blood properties. The data and fitted model parameters presented here can be used for calibration of future MRI investigations of fetal and neonatal blood physiology.

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