Abstract #2831

Fast Fluid Suppressed T1ρ Imaging of the Human Brain

Eberhard Daniel Pracht¹ and Tony Stöcker^1,2

¹German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany, ²University of Bonn, Department of Physics and Astronomy, Bonn, Germany

The longitudinal relaxation time in the rotating frame (T_1ρ) is a non-invasive biomarker, which is sensitive to slow macromolecular interactions. It might potentially be useful to detect pathological changes in neurodegenerative diseases such as Alzheimer’sDisease. However, long scan times and high SAR limit the application of this technique in a routine setting. Furthermore, high CSF signal modulates the image intensity at CSF/tissue boundaries leading to an overestimation of T1ρ in these regions. To overcome these issues we developed a fast and robust approach to assess T_1ρ in the human brain at high image resolution.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.