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Abstract #2836

Myelin Water Imaging using 3D Radial multi-echo GRE acquisition

Hongpyo Lee1, Yoonho Nam2, Min-Oh Kim1, Dongyeob Han1, Sung-Min Gho1, and Dong-Hyun Kim1

1School of Electrical and Electronic Engineering, Yonsei University, Soeul, Korea, Republic of, 2Department of Radiology, Seoul St. Mary Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of

Recently, myelin water fraction was investigated using multi-echo GRE data. In case of complex model fitting for MWF, only a small fraction of the total signal is used, small artifacts caused by physiological motion can induce severe noise in MWF. To overcome this problem, radial trajectory which is known to have robustness against object motion can be used. Also, this trajectory has the additional advantage of acquiring the more center of k-space than Cartesian trajectory which is helpful for detecting accurate T2* decay curve, and it may provide higher SNR and improved quantification. In this abstract, we demonstrated that the radial acquisition can reduce artifacts and improve image quality in MWF.

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