Abstract #2842

The Absence of Phase Information in the Signal-Deprived Image Background is an Important Source of Error in Susceptibility Mapping

Russell Dibb^1,2 and Chunlei Liu^3,4

¹Center for In Vivo Microscopy, Duke University, Durham, NC, United States, ²Biomedical Engineering, Duke University, Durham, NC, United States, ³Brain Imaging & Analysis Center, Duke University, Durham, NC, United States, ⁴Radiology, Duke University, Durham, NC, United States

Susceptibility mapping is limited in part due to reconstruction artifacts spawning from errors in tissue frequency data. Through simulations of susceptibility tensor imaging (STI) data, we show that a lack of phase information in the image background (where there is typically no signal) engenders artifacts in reconstructed susceptibility property maps. These errors are most egregious in the boundary regions of the object and affect mean susceptibility, susceptibility anisotropy, and tissue structure orientation measurements. Greater understanding of susceptibility mapping artifacts will aid in developing the tools necessary for accurate and reliable susceptibility imaging techniques.

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