Abstract #2841

Susceptibility Changes in Dentate Nucleus on Quantitative Susceptibility Mapping due to serial GBCAs administration.

Takuya Hinoda¹, Yasutaka Fushimi¹, Tomohisa Okada^1,2, Tsutomu Okada¹, Akira Yamamoto¹, and Togashi Kaori¹

¹Radiology, Graduate school of Medicine, Kyoto University, Kyoto, Japan, ²Human Brain Research Center, Graduate school of Mediine, Kyoto University, Kyoto, Japan

Gadolinium-based contrast agents (GBCAs) have been widely used for contrast material-enhanced magnetic resonance (MR) imaging. However, gadolinium accumulation in the dentate nucleus (DN) has gained attention due to recent studies. In this study, we retrospectively evaluated the susceptibility values of DN, using quantitative susceptibility mapping. The susceptibility values of the patients with GBCA administration were significantly higher than those of normal controls.

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