Abstract #2934

Assessment of Pleural Effusion in Dengue Fever

Therese Sjoholm¹, Benjamin A Thomas¹, Yin Mo², Louisa Sun², Ashley St. John³, Paul Anantharajah Tambyah², and John J Totman¹

¹A*STAR-NUS Clinical Imaging Research Centre, Singapore, Singapore, ²Department of Medicine, National University Hospital Singapore, Singapore, Singapore, ³Duke-NUS Graduate Medical School, Singapore, Singapore

In this study we assess the feasibility of using MRI for measurement of pleural effusion in Dengue Fever. 30 subjects with confirmed Dengue infection were scanned using T2-weighted HASTE MRI and chest x-rays (CXRs) at baseline and 4-8 days follow-up. Fluid accumulation in the pleural cavity was assessed for both modalities. For MRI, significantly different fluid accumulations were measured between baseline and follow-up (p=0.002). The fluid accumulations were all below the detectability limit of CXR. As such, MRI provides a sensitive measurement of pleural effusion in dengue fever and can be used to track fluid accumulation over time.

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