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Abstract #2943

The potentiality of MR T1rho as a biomarker for liver fibrosis evaluation

shuangshuang xie1, qing li1, yu zhang2, wenjing hou1, yue cheng1, and wen shen1

1Radiology, Tianjin First Center Hospital, Tianjin, China, People's Republic of, 2Philips healthcare, Beijing, China, People's Republic of

This study evaluated the potential of T1rho for liver fibrosis evaluation and to explore the best TSL points with good B0 and B1 inhomogeneity. Thirteen healthy control subjects and eight patients with clinically diagnosed liver fibrosis were scanned 3D b-TEF sequence. T1rho map were constructed by using 7-TSLs, 6-TSLs or 3-TSLs and compared between groups. Our results showed both 7-TSLs and 6-TSLs had moderate diagnostic efficacy, and AUC of 7-TSLs was slightly higher than 6-TSLs. We conclude 7-TSLs and 6-TSLs are recommended for the diagnosis of liver fibrosis, and 7-TSLs has slightly higher diagnostic performance.

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