This study evaluated the potential of T1rho for liver fibrosis evaluation and to explore the best TSL points with good B0 and B1 inhomogeneity. Thirteen healthy control subjects and eight patients with clinically diagnosed liver fibrosis were scanned 3D b-TEF sequence. T1rho map were constructed by using 7-TSLs, 6-TSLs or 3-TSLs and compared between groups. Our results showed both 7-TSLs and 6-TSLs had moderate diagnostic efficacy, and AUC of 7-TSLs was slightly higher than 6-TSLs. We conclude 7-TSLs and 6-TSLs are recommended for the diagnosis of liver fibrosis, and 7-TSLs has slightly higher diagnostic performance.
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