Abstract #2944

Measurement of Liver Perfusion using Pseudo-Continuous Arterial Spin Labeling with Background Suppression: Approaches to Separate Portal-Venous and Arterial Perfusion

Petros Martirosian¹, Rolf Pohmann², Christina Schraml³, Holger Schmidt³, Nina F Schwenzer³, Martin Schwartz¹, Klaus Scheffler², Konstantin Nikolaou³, and Fritz Schick¹

¹Section on Experimental Radiology, University of Tübingen, Tübingen, Germany, ²Max Planck Institute for Biological Cybernetics, Tübingen, Germany, ³Department of Diagnostic and Interventional Radiology, University Hospital of Tübingen, Tübingen, Germany

The separation of portal-venous and hepatic arterial blood supply is important for the evaluation of chronic liver diseases and the characterization of liver lesions. The aim of this study was to investigate the capability of a pseudo-continuous arterial spin labeling sequence, to separate arterial and portal venous perfusion of the liver using a background suppression technique and different tagging plane orientations. It was demonstrated that the presented method provides high quality perfusion images of the liver without application of intravenous contrast agent and offers promising approaches for the separation of arterial and portal-venous perfusion fractions.

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