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Abstract #2974

FDG-PET-MR acquisition in systemic sclerosis for the assessment of gastrointestinal involvement: a pilot study

Stephanie Marchesseau1, Sue-Ann P.L Ng2, Andrea H.L. Low2,3, YT Wang4, Jamie X.M Ho1, Josh D. Schaefferkoetter1, and John J. Totman1

1Clinical Imaging Research Centre, NUS, Singapore, Singapore, 2Departement of Rheumatology and Immunology, SGH, Singapore, Singapore, 3Duke-National University, Singapore, Singapore, 4Department of Gastroenterology and Hepatology, SGH, Singapore, Singapore

Systemic sclerosis (SSc) is a multi-system disease characterized by immune dysregulation, fibrosis and vascular damage that affects the gastrointestinal tract in most patients. In this study, we investigate simultaneous FDG-PET/MR imaging for the diagnosis of SSc GIT involvement. Our preliminary results show that FDG-PET can detect inflammation in the bowels while T1 MOLLI mapping could be able to distinguish healthy from fibrotic GIT tissue.

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