Abstract #2975

Rectal Cancer: Apparent Diffusion Coefficient Value and Clinical-Pathologic Factors Associated with Local Recurrence or Distant Metastases

Yoshifumi Noda¹, Satoshi Goshima¹, Hideto Tomimatsu¹, Haruo Watanabe¹, Hiroshi Kawada¹, Nobuyuki Kawai¹, Hiromi Ono¹, Masayuki Matsuo¹, and Kyongtae T Bae²

¹Radiology, Gifu University Hospital, Gifu, Japan, ²Radiology, University of Pittsburgh Medical Center, Pittsburgh, PA, United States

To determine the ADC value and clinical-pathologic risk factors associated with postoperative local recurrence or distant metastases in patients with rectal cancer. The plasmatic CA19-9 level (P = 0.0027), pathological N stage (P = 0.0018), lymphatic invasion (P < 0.0001), and ADC value (P = 0.0076) were independently associated with postoperative local recurrence or distant metastases in the patients with rectal cancer. Among the several indicators, the tumor ADC values and plasmatic CA19-9 level can be useful for the preoperative prediction of high risk cases for postoperative local recurrence or distant metastases in patients with rectal cancer.

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