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Abstract #3001

Dual-pathway sequences for MR thermometry: When and where to use them

Pelin Aksit Ciris1, Cheng-Chieh Cheng2, Chang-Sheng Mei3, Lawrence P. Panych2, and Bruno Madore2

1Department of Biomedical Engineering, Akdeniz University, Antalya, Turkey, 2Department of Radiology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, United States, 3Department of Physics, Soochow University, Taipei, Taiwan

Dual-pathway sequences have been proposed to improve the temperature-to-noise-ratio (TNR) in MR thermometry. The present work establishes how much improvement these sequences may bring for various tissue types. Simulation results were validated against analytical equations, phantom and in vivo human results. PSIF-FISP thermometry allowed TNR improvements for kidney, pelvis, spleen or gray matter, and up to 2-3 fold reductions in TR with 20% TNR gains were achievable. Further TNR benefits are expected for heated tissues, due to heating-related changes in relaxation rates. In other tissue types such as liver, muscle or pancreas improvements were observed only for short TR settings.

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