Abstract #3008

Towards Fast Diffusion-Sensitized MR Imaging of the Eye and Orbit with High Anatomic Fidelity: Combining a Segmented RARE variant with Inner Volume Imaging

Katharina Paul¹, Till Huelnhagen¹, Oliver Stachs², and Thoralf Niendorf^1,3

¹Berlin Ultrahigh Field Facility (B.U.F.F), Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany, ²Department of Ophthalmology, University Medicine Rostock, Rostock, Germany, ³Experimental and Clinical Research Center, a joint cooperation between the Charité Medical Faculty and the Max-Delbrueck-Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany

Diffusion-weighted imaging of the eye and orbit is an emerging MRI application to provide guidance during diagnostic assessment and treatment of ophthalmological diseases. It has been shown that RARE based diffusion-sensitized imaging (ms-RARE) provides images free of geometric distortions. Though, artifacts induced by involuntary eye motion remain a concern. Applying inner volume imaging (IVI) offers the possibility to shorten acquisition times by reducing the number of acquired phase encoding lines. This study examines the applicability of IVI in conjunction with ms-RARE with the goal to reduce the propensity to bulk eye motion in diffusion-sensitized ophthalmic imaging.

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