Abstract #3014

Time-dependent diffusion on in vivo human brain data from the Connectom scanner

Uran Ferizi¹, Claudia Wheeler-Kingshott², Daniel Alexander³, and Jose Raya¹

¹Department of Radiology, New York University School of Medicine, New York, NY, United States, ²Institute of Neurology, University College London, London, United Kingdom, ³Department of Computer Science, University College London, London, United Kingdom

Diffusion MRI models for brain microstructure do not currently incorporate time-dependent diffusivity. Previous studies with ex vivo tissue (muscle and brain) have observed such dependency. The advent of high diffusion gradient scanners have enabled us to probe the tissue to unprecedented. Here we examine and observe the time dependency of the measured diffusion using data from the live human brain.

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