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Abstract #3014

Time-dependent diffusion on in vivo human brain data from the Connectom scanner

Uran Ferizi1, Claudia Wheeler-Kingshott2, Daniel Alexander3, and Jose Raya1

1Department of Radiology, New York University School of Medicine, New York, NY, United States, 2Institute of Neurology, University College London, London, United Kingdom, 3Department of Computer Science, University College London, London, United Kingdom

Diffusion MRI models for brain microstructure do not currently incorporate time-dependent diffusivity. Previous studies with ex vivo tissue (muscle and brain) have observed such dependency. The advent of high diffusion gradient scanners have enabled us to probe the tissue to unprecedented. Here we examine and observe the time dependency of the measured diffusion using data from the live human brain.

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