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Abstract #3048

Correlation Time Diffusion Brain Mapping at 1.5T vs. 3.0T

Hernan Jara1, Arnaud Guidon2, Lloyd Estkowski3, Jorge A Soto1, and Osamu Sakai1

1Radiology, Boston University, Boston, MA, United States, 2Global MR Applications and Workflow, GE Healthcare, Boston, MA, United States, 3Global MR Applications and Workflow, GE Healthcare, Menlo Park, CA, United States

Purpose: To test the hypothesis that correlation time diffusion coefficient (DCT) MRI is not be dependent of the main magnetic field strength B0. Methods: A heathy volunteer was scanned (head) at 1.5T and 3.0T with the same diffusion mapping capable scans: quadra-FSE for DCT mapping and DW-SE-sshEPI for DPFG mapping. Results: Despite the B0 dependent shifts of the relaxation time (T1, T2) histograms, the DCT, DPFG, and PD histograms do not exhibited significant B0 shifts. Conclusion: The correlation time diffusion coefficient is theoretically and experimentally a genuine physical property inherent to biological tissue and independent of experimental variables including B0.

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