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Abstract #3049

Non-invasive characterization of BI-RADS 4/5 X-ray mammography findings using unenhanced breast MRI with fusion of diffusion weighted and morphological T2-weighted images

Sebastian Bickelhaupt1, Jana Tesdorff1, Frederik Bernd Laun2, Wolfgang Lederer3, Heidi Daniel4, Tristan Amseln Kuder2, Susanne Teiner3, Stefan Delorme2, and Heinz-Peter Schlemmer2

1Department of Radiology, German Cancer Research Center, Heidelberg, Germany, 2Department of Medical Physics in Radiology, German Cancer Research Center, Heidelberg, Germany, 3Radiological Practice at the ATOS Clinic Heidelberg, Heidelberg, Germany, 4Radiology Center Mannheim (RZM), Mannheim, Germany

Additive unenhanced breast MRI prior to biopsy might reduce false positive x-ray mammograms. Therefore we evaluated the adjunctive diagnostic value of unenhanced breast MRI with image fusion of DWI and T2-weighted images and compared it to a side-by-side analysis of the sequences. 30 patients were included undergoing a 1.5 T breast MRI examination prior biopsy. We found that reading DWI/T2w-fused images alone decreased the accuracy (81.6% ±2.8%) compared to the side-by-side analysis (91.6% ± 2.3%) and significantly reduced the reader confidence significantly (p<0.001). Therefore fused image series should currently be considered always in addition to morphologic images since they could miss important morphologic information.

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