Abstract #3049

Non-invasive characterization of BI-RADS 4/5 X-ray mammography findings using unenhanced breast MRI with fusion of diffusion weighted and morphological T2-weighted images

Sebastian Bickelhaupt¹, Jana Tesdorff¹, Frederik Bernd Laun², Wolfgang Lederer³, Heidi Daniel⁴, Tristan Amseln Kuder², Susanne Teiner³, Stefan Delorme², and Heinz-Peter Schlemmer²

¹Department of Radiology, German Cancer Research Center, Heidelberg, Germany, ²Department of Medical Physics in Radiology, German Cancer Research Center, Heidelberg, Germany, ³Radiological Practice at the ATOS Clinic Heidelberg, Heidelberg, Germany, ⁴Radiology Center Mannheim (RZM), Mannheim, Germany

Additive unenhanced breast MRI prior to biopsy might reduce false positive x-ray mammograms. Therefore we evaluated the adjunctive diagnostic value of unenhanced breast MRI with image fusion of DWI and T2-weighted images and compared it to a side-by-side analysis of the sequences. 30 patients were included undergoing a 1.5 T breast MRI examination prior biopsy. We found that reading DWI/T2w-fused images alone decreased the accuracy (81.6% ±2.8%) compared to the side-by-side analysis (91.6% ± 2.3%) and significantly reduced the reader confidence significantly (p<0.001). Therefore fused image series should currently be considered always in addition to morphologic images since they could miss important morphologic information.

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