Abstract #3059

Improvement of probabilistic tractography of the corticospinal tract in human brain

David Neil Manners¹, Claudia Testa¹, Stefania Evangelisti¹, Stefano Zanigni¹, Mariagrazia Popeo^2,3, Caterina Tonon¹, and Raffaele Lodi¹

¹Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy, ²Istituto Italiano di Tecnologia, Rovereto, Italy, ³Center for Neurosciences and Cognitive Systems, University of Trento, Rovereto, Italy

We performed an along tract analysis of the cortico-spinal tract in a group of healthy subjects using a probabilistic tractography algorithm. We were able to evaluate CST reconstruction along the tract using appropriate performance metrics, based on the congruence of fibre paths in the subject population, and the presence or absence of fibre tracks identified as originating from the precentral gyrus. The method was compatible with clinical protocols given spatial definition and tract localization obtained.

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