Abstract #3091

Diffusion Microstructure Imaging With High-Performance Head-Only Gradient: Preliminary Results

Ek T Tan¹, Jonathan I Sperl², Miguel Molina Romero^2,3, Seung-Kyun Lee¹, Matt A Bernstein⁴, and Thomas KF Foo¹

¹GE Global Research, Niskayuna, NY, United States, ²GE Global Research, Munich, Germany, ³Technical University of Munich, Munich, Germany, ⁴Mayo Clinic, Rochester, MN, United States

A high-performance head-only gradient coil (G_max=80 mT/m, SR=700 T/m/s) allows diffusion imaging at substantially shorter echo-time and echo-spacing than conventional whole-body gradient coil systems. This greatly benefits microstructure imaging with diffusion EPI, providing reduced echo spacing by up-to two-fold and shorter TE by up-to 30%. Imaging results demonstrate reduced distortion and improved white matter SNR. Preliminary results on axonal radius mapping with high b-value imaging (up-to b=12,000 s/mm²) demonstrate the feasibility of 2 mm-isotropic imaging with the head-gradient.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.