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Abstract #3096

Intravoxel Incoherent Motion in Normal Pituitary Gland: Initial Study with Turbo Spin-echo Diffusion-weighted Imaging

Kiyohisa Kamimura1, Masanori Nakajo1, Yoshihiko Fukukura1, Takashi Iwanaga2, Tomonori Saito2, Masashi Sasaki2, Takuro Fujisaki2, Atsushi Takemura3, Tomoyuki Okuaki 3, and Takashi Yoshiura1

1Radiology, Kagoshima University Medical and Dental Hospital, Kagoshima, Japan, 2Clinical Engineering Department Radiation Section, Kagoshima University Hospital, Kagoshima, Japan, 3Philips Electronics Japan, Tokyo, Japan

Our purpose was to evaluate the feasibility of intravoxel incoherent motion (IVIM) assessment based on turbo spin-echo diffusion-weighted imaging (TSE-DWI) in the normal pituitary gland. In a validation study using normal brain white matter (WM), Bland-Altman analyses revealed fair to good agreement with conventional echo-planar-based DWI (EP-DWI) in the true diffusion coefficient (D) and perfusion fraction (f). In 7 volunteers, both D and f in the anterior pituitary lobe were significantly higher than those in WM, being consistent with high microvascular density in the pituitary gland. Results demonstrated that IVIM assessment based on TSE-DWI in the pituitary gland is feasible.

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