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Abstract #3098

Anisotropy measure from High angular resolution diffusion imaging Data Using Higher Order Diffusion Tensor model

Getaneh Bayu Tefera1 and Ponnada A. Narayana1

1Diagnostic & Interventional Imaging, University of Texas at Houston, Houston, TX, United States

Different anisotropy indices such as generalized anisotropy (GA) and generalized fractional anisotropy (GFA) for HARDI data have been reported, but they have their own limitations. Here we propose a new anisotropy measure (HFA) for the HARDI data that is rotationally invariant. The new proposed measure is compared with GA and GFA using the contrast-to-noise ratio and coefficient of variation as the metrics for three white matter regions. HFA and GFA have shown better CNR than FA and GA in two and three crossing regions. The results described above were very similar across all the five subjects.

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