Abstract #3113

Comprehensive comparison of in- and ex-vivo whole heart fiber architecture: similar yet different

Martijn Froeling¹, Gustav J Strijkers², Laura W M Vergoossen³, Eibert A ten Hove³, Aart J Nederveen⁴, Tim Leiner¹, and Peter R Luijten¹

¹Radiology, UMC Utrecht, Utrecht, Netherlands, ²Biomedical Engineering & Physics, AMC Amsterdam, Amsterdam, Netherlands, ³Biomedical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands, ⁴Radiology, AMC Amsterdam, Amsterdam, Netherlands

The aim of this study was to provide a comprehensive description of whole heart in-vivo myocardial fiber architecture using the fiber architecture matrix, and to validate results using ex-vivo and simulated data. We showed that whole heart fiber architecture described by the FAM can be obtained from in-vivo DWI. However, compared to ex-vivo data the direction of ε₂ and ε₃ are exchanged.

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