Abstract #3117

Right Ventricular Myofiber Architecture

Benoit Scherrer¹, Amara Majeed², Onur Afacan¹, Jolene M. Singh¹, Simon K. Warfield¹, and Stephen P. Sanders²

¹Department of Radiology, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States, ²Departments of Cardiology and Pathology, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States

While the left ventricle (LV) myofiber architecture has been studied extensively, there have been fewer studies of right ventricle (RV) myofiber architecture, and there is no established convention for reporting RV myofiber anatomy. Establishing the normal RV myofiber architecture is critical to facilitate our understanding of the impact of congenital microstructural defects in diseased hearts. In this work, we fixed a juvenile swine heart and imaged it with magnetic resonance diffusion compartment imaging (MR-DCI). We describe the detailed myofiber pattern of the RV with both MR-DCI and stained histological microscopy, and propose a standardized convention for describing the myofiber anatomy.

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