Abstract #3124

Biventricular Cardiac Mechanics in Healthy Subjects using 3D Spiral Cine DENSE and Mesh-Free Strain Analysis

Jonathan D Suever^1,2, Gregory J Wehner³, Christopher M Haggerty^1,2, Linyuan Jing^1,2, David K Powell³, Sean M Hamlet⁴, Jonathan D Grabau², Dimitri Mojsejenko², and Brandon K Fornwalt^1,2,3

¹Institute for Advanced Application, Geisinger Health System, Danville, PA, United States, ²Pediatrics, University of Kentucky, Lexington, KY, United States, ³Biomedical Engineering, University of Kentucky, Lexington, KY, United States, ⁴Electrical Engineering, University of Kentucky, Lexington, KY, United States

Cardiac mechanics have been extensively characterized in the left ventricle (LV). However, the right ventricle (RV) is rarely studied due to both acquisition and post-processing challenges. In this study, we combined 3D displacement-encoded (DENSE) imaging with custom post-processing that utilizes a local coordinate system to extract advanced measures of cardiac mechanics in an effort to characterize healthy biventricular function. We found that torsion as well as circumferential and longitudinal strain vary throughout the RV, but globally were comparable to their LV counterparts. This data can be used to better understand how biventricular function is disrupted by disease.

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