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Abstract #3127

Effect of Respiratory Suspension on the Computation of Left Ventricular (LV) Volume and Rate of Volume Change (dV/dt)-based Diastolic Indices with Echocardiography as a Reference

Amol Pednekar1, Jiming Zhang2, Debra Dees3, Benjamin Y Cheong3, and Raja Muthupillai3

1Phillips Healthcare, Cleveland, OH, United States, 2Diagnostic and interventional Radiology, CHI St Luke's Health, Houston, TX, United States, 3Diagnostic and Interventional Radiology, CHI St Luke's Health, Houston, TX, United States

Diastolic functional indices based on trans-mitral blood flow velocities are pre-load dependent and early diastolic filling can be diminished by activities such as inspiration or Valsalva maneuver. Cardiac cine MR images are typically acquired during suspended respiration and thus could induce systemic bias. In this study, we evaluate the impact of respiratory suspension on the computation of volume-based diastolic indices using peak velocity-based Doppler echo measurements as the reference. The volume based diastolic indices derived from high temporal resolution cine MR correlated well with velocity based E/A ratio from echo while indicating the direct impact of respiratory suspension.

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