Abstract #3151

3D Free Breathing Whole Heart T1 mapping at 3 T

Rui Guo¹, Zhensen Chen¹, Jianwen Luo¹, and Haiyan Ding¹

¹Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China, People's Republic of

In this study, we developed a free-breathing, three-dimensional (3D) T1 mapping method at 3T based on the saturation-prepared, inversion-prepared radiofrequency-spoiled gradient echo (SPGR) sequence, which achieved 3D T1 maps with whole heart coverage. Excellent correlation for the T1 values typically observed in myocardium pre and post contrast was obtained with little residual (R² = 0.99) and a regression slope 0.93. Homogeneous T1 maps were obtained from in-vivo study. Whole left ventricle T1 mapping was finished in around ~10 minutes with about 40% navigator efficiency without using any parallel imaging. Measured normal myocardium T1 values were comparable to those previously published.

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