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Abstract #3156

Automatic extracellular volume fraction mapping in the myocardium: multiple initial T1 values and deformable image registration combined with LV segmentation

Chiao-Ning Chen1, Hsiao-Hui Huang1, Ming-Ting Wu2, and Teng-Yi Huang1

1Electrical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan, 2Radiology, Kao-Hsiung Veterans General Hospital, Kao-Hsiung, Taiwan

This study attempted to improve the accuracy of T1 fitting and image registration for automatic extracellular volume fraction mapping. We proposed to use multiple initial values in the T1 fitting procedure and the results prominently exhibited less errors. For the image registration, we first performed the automatic segmentation of left-ventricle (LV) walls based on an image synthesis approach and then used the obtained LV masks for the deformable image registration. The results supported that the method significantly improved the overlap rate between the pre- and postcontrast images as well as the accuracies of the obtained ECV maps.

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