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Abstract #3170

Myocardial T1-map-derived extracellular volume fraction (ECV) measurement can represent the disease severity and prognostic information in patients with dilated cardiomyopathy (DCM)

Yoshiaki Morita1, Naoaki Yamada1, Emi Tateishi2, Teruo Noguchi2, Masahiro Higashi1, and Hiroaki Naito1

1Department of Radiology, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan, 2Division of Cardiology, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan

Myocardial fibrosis is closely related to clinically evident cardiac dysfunction and worse outcomes, such as heart failure and arrhythmia. Therefore, non-invasive methods, which can reliably quantify fibrosis, would be preferable. In this study, we demonstrated that T1-map-derived ECV measurement is a significant independent predictor of major adverse cardiovascular events (MACEs) when compared with the presence of LGE and other risk factors. ECV may thus represent a novel prognostic indicator in patients with DCM.

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