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Abstract #3171

Accelerated Multi Echo based Correlated spectroscopic imaging of calf muscle in three spatial dimensions

Manoj Kumar Sarma1, Zohaib Iqbal1, Rajakumar Nagarajan1, and M. Albert Thomas1

1Radiological Sciences, UCLA School of Medicine, Los angeles, Los Angeles, CA, United States

Multi-echo based echo-planar correlated spectroscopic imaging (ME-EP-COSI) has been an innovative method to study muscle lipid content in T2D and a variety of other metabolic conditions. In this study we implemented accelerated ME-EP-COSI and validated in a corn oil phantom and in healthy human calf muscle. Both phantom and human calf muscle results show that 5D ME-EP-COSI has the potential to be a powerful tool for human calf muscle examination. Further studies will investigate various pathologies, including obesity and type 2 diabetes, using the 5D ME-EP-COSI method.

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