Abstract #3171

Accelerated Multi Echo based Correlated spectroscopic imaging of calf muscle in three spatial dimensions

Manoj Kumar Sarma¹, Zohaib Iqbal¹, Rajakumar Nagarajan¹, and M. Albert Thomas¹

¹Radiological Sciences, UCLA School of Medicine, Los angeles, Los Angeles, CA, United States

Multi-echo based echo-planar correlated spectroscopic imaging (ME-EP-COSI) has been an innovative method to study muscle lipid content in T2D and a variety of other metabolic conditions. In this study we implemented accelerated ME-EP-COSI and validated in a corn oil phantom and in healthy human calf muscle. Both phantom and human calf muscle results show that 5D ME-EP-COSI has the potential to be a powerful tool for human calf muscle examination. Further studies will investigate various pathologies, including obesity and type 2 diabetes, using the 5D ME-EP-COSI method.

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