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Abstract #3290

Multi-site, multi-vendor comparison of T1 measurement using ISMRM/NIST system phantom

Kathryn E Keenan1, Karl F Stupic1, Michael A Boss1, Stephen E Russek1, Tom L Chenevert2, Pottumarthi V Prasad3, Wilburn E Reddick4, Kim M Cecil5, Jie Zheng6, Peng Hu7, Edward F Jackson8, and Ad Hoc Committee for Standards in Quantitative MR9

1Physical Measurement Laboratory, National Institute of Standards and Technology, Boulder, CO, United States, 2University of Michigan, Ann Arbor, MI, United States, 3NorthShore University Health System, Evanston, IL, United States, 4St. Jude Children's Research Hospital, Memphis, TN, United States, 5Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States, 6Washington University in St. Louis, St. Louis, MO, United States, 7University of California Los Angeles, Los Angeles, CA, United States, 8University of Wisconsin, Madison, WI, United States, 9ISMRM, Berkeley, CA, United States

We used the ISMRM/NIST system phantom to assess variations of T1 measurements across MRI systems at 1.5 T and 3 T, to determine the repeatability and reproducibility of the T1 measurements. This study demonstrates that T1 variations from NMR-measured value are correlated site-to-site within a vendor and by position within the head coil. The deviation from the NMR-measured values is greater at 3 T than at 1.5 T. The VFA data has a larger variation than IR; B1 inhomogeneity could contribute to the larger systematic error in VFA measurements. The ISMRM/NIST system phantom is an excellent tool for evaluating multi-site MRI acquisition protocols.

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