Abstract #3290

Multi-site, multi-vendor comparison of T1 measurement using ISMRM/NIST system phantom

Kathryn E Keenan¹, Karl F Stupic¹, Michael A Boss¹, Stephen E Russek¹, Tom L Chenevert², Pottumarthi V Prasad³, Wilburn E Reddick⁴, Kim M Cecil⁵, Jie Zheng⁶, Peng Hu⁷, Edward F Jackson⁸, and Ad Hoc Committee for Standards in Quantitative MR⁹

¹Physical Measurement Laboratory, National Institute of Standards and Technology, Boulder, CO, United States, ²University of Michigan, Ann Arbor, MI, United States, ³NorthShore University Health System, Evanston, IL, United States, ⁴St. Jude Children's Research Hospital, Memphis, TN, United States, ⁵Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States, ⁶Washington University in St. Louis, St. Louis, MO, United States, ⁷University of California Los Angeles, Los Angeles, CA, United States, ⁸University of Wisconsin, Madison, WI, United States, ⁹ISMRM, Berkeley, CA, United States

We used the ISMRM/NIST system phantom to assess variations of T1 measurements across MRI systems at 1.5 T and 3 T, to determine the repeatability and reproducibility of the T1 measurements. This study demonstrates that T1 variations from NMR-measured value are correlated site-to-site within a vendor and by position within the head coil. The deviation from the NMR-measured values is greater at 3 T than at 1.5 T. The VFA data has a larger variation than IR; B1 inhomogeneity could contribute to the larger systematic error in VFA measurements. The ISMRM/NIST system phantom is an excellent tool for evaluating multi-site MRI acquisition protocols.

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