1State Key Lab Magnet Resonance & Atom & Mol Phys, Wuhan Inst Phys & Math, Chinese Acad Sci, Wuhan, China, People's Republic of, 2School of Physics, Huazhong University of Science and Technology, Wuhan, China, People's Republic of
In
hyperpolarized gas MRI, the accurate flip angle calibration and T1
measurements are important. Traditional flip angle calibration methods are
time-consuming and suffer from polarization losses during T1
relaxation. In this study, we propose a method to simultaneously calibrate flip
angles and measure T1in vivo
during a breath-hold time of less than 4 seconds. The so-called single-breath method
is magnitude based and simple to use. We demonstrate the accuracy of this
method and contrast it with traditional methods. The results of the calibration
verified that it is robust and repeatable.
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