Abstract #3318

Motion Range Grouping of Brain Regions Based on Displacement Measured with Displacement Encoding with Stimulated Echoes (DENSE)

Xiaodong Zhong¹, Tucker Lancaster², Zihan Ye³, Deqiang Qiu², Brian M. Dale⁴, John N. Oshinski^2,3, and Amit Saindane²

¹MR R&D Collaborations, Siemens Healthcare, Atlanta, GA, United States, ²Department of Radiology and Imaging Sciences, Emory University, Atlanta, GA, United States, ³Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, United States, ⁴MR R&D Collaborations, Siemens Healthcare, Cary, NC, United States

In this work, we demonstrated that the DENSE technique can be used to measure and group motion of different brain regions. Preliminary results in 9 volunteers showed that the brain regions near the CSF (midbrain, pons, medulla and optic chiasm) had larger motion magnitude than regions far away (frontal lobe, occipital lobe, parietal lobe and cerebellum). DENSE enables us to investigate brain motion to a level of detail that has not been previously possible. The findings in this study may bring new insight into brain motion and provide useful information to improve potential imaging and therapy techniques.

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