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Abstract #3318

Motion Range Grouping of Brain Regions Based on Displacement Measured with Displacement Encoding with Stimulated Echoes (DENSE)

Xiaodong Zhong1, Tucker Lancaster2, Zihan Ye3, Deqiang Qiu2, Brian M. Dale4, John N. Oshinski2,3, and Amit Saindane2

1MR R&D Collaborations, Siemens Healthcare, Atlanta, GA, United States, 2Department of Radiology and Imaging Sciences, Emory University, Atlanta, GA, United States, 3Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, United States, 4MR R&D Collaborations, Siemens Healthcare, Cary, NC, United States

In this work, we demonstrated that the DENSE technique can be used to measure and group motion of different brain regions. Preliminary results in 9 volunteers showed that the brain regions near the CSF (midbrain, pons, medulla and optic chiasm) had larger motion magnitude than regions far away (frontal lobe, occipital lobe, parietal lobe and cerebellum). DENSE enables us to investigate brain motion to a level of detail that has not been previously possible. The findings in this study may bring new insight into brain motion and provide useful information to improve potential imaging and therapy techniques.

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